Monday, July 19, 2010

Huntington's Disease-Autosomal Dominant

To the bottom, the brain of a person with Huntington’s disease (top) vs. a normal brain (bottom)



The nerves are slowly destroyed.
-Huntington’s disease (HD) occurs when there is a large amount of CAG codon repeats within the Huntington gene.
-The disease is located on chromosome 4 at 4p16.3
-It begins at middle age (30’s or 40’s) and can cause premature death.


Symptoms (just a few)
-Difficulty moving
-Can’t speak very well
-loss of physical coordination
It is most common with European Ancestry (5 in 100,000 people)
-There is no cure. The progress can’t even be slowed. There is research for a cure being constructed.
Treatment can reduce some of the affects.

Lifestyle-depending on the number of codon repeats, influences the lifespan of a person
In order to stay healthy for as long as possible
-Speech therapy
-Maintain physical activity
-Keep up proper nutrition
-adequate fluids

1 comment:

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